Doctor Scott and the Witch Doctor have been individually working on a new cure that potentially could help millions of sick people every year. There is only one problem with their approach; neither of them can seem to work together to finish the research. Things get even worse after Ursula and Magnolia got sick and only their cure could help them. A heated confrontation ensues which sends their research flying high into the air where a curious Tookie Tookie grabs it and flies away. As the precious papers fly into the distance the pages begin to fall and scatter throughout the jungle. With the papers now hidden in some of the most dangerous terrain imaginable, their only hope is George. George and his friends set out on a grand adventure to rescue the precious pages.